3,3'-Diindolylmethane
3, 3-Diindolylmethane (DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables. At the present time, DIM is used to treat Recurring Respiratory Papillomatosis, a rare respiratory disease with tumors in the upper respiratory tracts caused by the Human Papilloma Virus.
Features
English Name: 3,3'-Diindolylmethane
Other Name: 3-(1H-Indol-3-ylmethyl)-1H-indole; 3,3'-Methylenebis-1H-indole; DIM
Appearance: White or almost white powder
Basic Information
English Name: 3,3'-Diindolylmethane
Other Name: 3-(1H-Indol-3-ylmethyl)-1H-indole; 3,3'-Methylenebis-1H-indole; DIM
Appearance: White or almost white powder
CAS No.: 1968-05-4
Molecular formula: C17H14N2
Function
Abnormal growth of cells of the cervix (cervical dysplasia). Early research suggests that taking a specific diindolylmethane product (BioResponse-DIM by BioResponse) for 12 weeks does not improve markers of disease in women with cervical dysplasia.
Prostate cancer. Early research suggest that taking a specific diindolylmethane product (BioResponse-DIM) for 28 days lowers prostate-specific antigen (PSA) levels in men with prostate cancer. PSA levels can be used to measure the Progress of prostate cancer.
Abnormal growth of cells of the cervix (cervical dysplasia). Early research suggests that taking a specific diindolylmethane product (BioResponse-DIM by BioResponse) for 12 weeks does not improve markers of disease in women with cervical dysplasia.
Preventing uterine cancer.
Preventing colon cancer.
Preventing breast cancer.
Preventing prostate enlargement (benign prostatic hypertrophy, BPH).
Treating premenstrual syndrome (PMS).
Other conditions.
Application
1. Combats Cancer
DIM is potent at fighting cancer.
For example, DIM inhibited the growth of mammary gland cell cancer, (via modulation of estrogen receptor α and AhR).
2. Reduces Inflammation
As a partial CB2 agonist, DIM may help with neuroinflammation by working on the endocannabinoid system. DIM can also protect against inflammation by acting on GPR84.DIM also has potent COX-2 inhibition properties.
3.Promotes Detoxification And Antioxidant Production
Through the activation of Aryl Hydrocarbon Receptors (AhR) and Nrf2 signaling pathways, DIM effectively increases detoxification and reduces inflammatory signaling
DIM can modulate AhR, which promotes transcription of genes that stimulate the expression of detoxification enzymes, including the phase I cytochrome P450 (CYP) family. It can also induce the transcription factor NRF2, which has strong anti-oxidant and detoxification properties.
Specifications Sheet
| Content | Specification |
| Appearance | Off-white to light yellow Powder |
| Assay(HPLC) | ≥99% |
| Melting Point | 96 -100°C |
| Loss on drying | ≤5.0% |
| Residual on Ignition | ≤0.5% |
| Bulk density (loose) | 0.15-0.45g/ml |
| Arsenic | ≤1ppm |
| Pb | ≤5ppm |
| Microbiological Control | |
| Total Plate Count | <500CFU/G |
| Mould &Yeast | <100CFU/G |
| E.Coli | Absent |
| Salmonella | Absent |
| Stahylococcus aureus | Absent |
| Pseudomona aeruginosa | Absent |
Shipping & Storage
Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Quality&Certifications
