Caffeic acid
Caffeic acid has been shown to inhibit carcinogenesis, although other experiments show possiblecarcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.
Features
Synonyms: 3,4-Dihydroxycinnamic Acid
CAS.NO: 331-39-5
Molecular Formula:C9H8O4
Molecular Weight: 180.16
Test Method And Purity:HPLC ≥98%
Basic Information
Product Name:Caffeic Acid
Synonyms: 3,4-Dihydroxycinnamic Acid
CAS.NO: 331-39-5
Molecular Formula:C9H8O4
Molecular Weight: 180.16
Test Method And Purity:HPLC ≥98%
Function
Caffeic acid has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.Caffeic acid also shows immunomodulatory and antiinflammtory activity.
Caffeic acid outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhanceAspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti- fungicide methods by supplementing trees with antioxidants.Another study also showed that CAPE suppresses acute immune and inflammatory responses and holds promise for therapeutic uses to reduce inflammation.
Application
Caffeic Acid and its derivative, Caffeic Acid Phenethyl Ester (CAPE) have shown tumor-shrinking properties. When an anti-cancer drug was being sought, Caffeic Acid and CAPE were derived from Burning Bush (Euonymus alatus). "The subcutaneous and oral administrations of CA and CAPE significantly reduced liver metastasis. These results confirm the therapeutic potential of the compounds and suggest that the anti-metastatic and anti-tumor effects of CA and CAPE are mediated through the selective suppression of MMP-9 enzyme activity and transcriptional down-regulation by the dual inhibition of NF-B as well as MMP-9 catalytic activity."
Caffeic Acid and chlorogenic acid from coffee beans both reduced DNA methylation in vitro in two lines of human cancer cells. DNA methylation contributes to the growth of tumors and regulates the epigenetics of cells that are passed along with DNA to future generations
Specifications Sheet
| Certificate of Analysis | ||
| Item | Specification | Result |
| Assay | 99% | 99.68% |
| Appearance | Light Yellow Powder | conforms |
| Odor | Characteristic | conforms |
| Taste | Characteristic | conforms |
| Particle Size | NLT 100% Through 80 mesh | conforms |
| Loss on Drying | <2.0% | 0.47% |
| Heavy metals | ||
| Total Heavy Metals | ≤10ppm | conforms |
| Arsenic | ≤3ppm | conforms |
| Lead | ≤3ppm | conforms |
| Microbiological Tests | ||
| Total Plate Count | ≤1000cfu/g | conforms |
| Total Yeast & Mold | ≤100cfu/g | conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
Shipping & Storage
Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Quality&Certifications
